I have used the MiniMed Quick Set Paradigm infusion set for the last couple years. Medtronic recommends that one changes their infusion set every 48-72 hours.
I am the kind of person who questions why I have to do an oil change every 3000 miles and not 5000 miles but think for the 670G it is important to follow these guidelines.
Any blockage on your infusion set and subsequent high glucose readings will most likely throw Auto Mode and it will take hours before you can go back into Auto Mode. This is such a pain especially in the middle of the night since you will also receive a barrage of notifications to rectify the situation.